Clinical markers of early disease
HD - Neuropsychological measures show impairment 2 years before the develop-ment of more
manifest motor disease. Findings suggest that these brief cognitive measures administered over time may capture early striatal
neural loss in HD.
Cognitive and Psychiatric Abnormalities - Excerpt from an article,
Huntington's Disease: Bridging Clinical and Basic Neurobiology", written in 1999 describing the cognitive and psychiatric
abnormalitites which may appear in Huntingotn's Disease.
Scientific article discussing the gray zone in genetic testing for Huntington's
Disease where the person, themself, may not get the disease but their offspring may still get it.
High incidence rate and absent family histories in one quarter of patients
newly diagnosed with Huntington disease in the UK. Research articles and discussion on Hunt-Dis/view comments
A Huntington's Disease Pedigree Using Direct Genetic Testing
|
Mapping Modifier Genes for Huntington's
Disease- University of Oxford collaboration
with Prof Nancy Wexler of Columbia University, performing a linkage genome scan to map loci which may modify the expression
of Huntington's Disease. 22 January, 2003
|
|
To describe the consequences of the identification of the Huntington's
disease (HD) mutation on predictive and prenatal testing.
Subtle changes among presymptomatic
HD - Among Huntington's disease gene carriers, subtle cognitive and
motor deficits precede the onset of sufficient neurological abnormality to warrant a clinical diagnosis of Huntington's disease. |
Michelle Fox, the Genetic Counselor with UCLA
Medical Center May 13,1999 Nightline discussion with Barbara Walters and other
esteemed guests
Other Resources
From NINDS:
|
